Manallack, David T. : rechercher sur Z-Library

Manallack, David T., Prankerd, Richard J., Yuriev, Elizabeth, Oprea, Tudor I., Chalmers, David K.

Année:

2011

Langue:

english

Fichier:

PDF, 953 KB

english, 2011

The significance of acid/base properties in drug discovery

Journal:

Chemical Society Reviews

Année:

2013

Langue:

english

Fichier:

PDF, 2.46 MB

english, 2013

Ten Simple Rules for Developing a MOOC

Manallack, David T., Yuriev, Elizabeth, Lewitter, Fran

Journal:

PLoS Computational Biology

Année:

2016

Langue:

english

Fichier:

PDF, 440 KB

english, 2016

Estimation of pKa Using Semiempirical Molecular Orbital Methods. Part 1: Application to Phenols and Carboxylic Acids.

Benjamin G. Tehan, Edward J. Lloyd, Margaret G. Wong, Will R. Pitt, John G. Montana, David T. Manallack, Emanuela Gancia

Journal:

Benjamin G. Tehan, Edward J. Lloyd, Margaret G. Wong, Will R. Pitt, Emanuela Gancia, David T. Manallack

Année:

2002

Langue:

english

Fichier:

PDF, 362 KB

english, 2002

Estimation of pKa Using Semiempirical Molecular Orbital Methods. Part 2: Application to Amines, Anilines and Various Nitrogen Containing Heterocyclic Compounds.

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 171 KB

english, 2002

ChemInform Abstract: Arylsulfonyl Hydroxamic Acids: Potent and Selective Matrix Metalloproteinase Inhibitors.

Andrew D. Baxter, Ranjev Bhogal, John Bird, John F. Keily, David T. Manallack, John G. Montana, David A. Owen, William R. Pitt, Robert J. Watson, Ruth E. Wills

Journal:

David T. Manallack, Will R. Pitt, Emanuela Gancia, John G. Montana, David J. Livingstone, Martyn G. Ford, David C. Whitley

Année:

2001

Fichier:

PDF, 30 KB

2001

Selecting Screening Candidates for Kinase and G Protein-Coupled Receptor Targets Using Neural Networks.

Journal:

David T. Manallack, Richard A. Hughes, Philip E. Thompson

Année:

2002

Fichier:

PDF, 26 KB

2002

The Next Generation of Phosphodiesterase Inhibitors: Structural Clues to Ligand and Substrate Selectivity of Phosphodiesterases

Journal:

David T. Manallack, Frank R. Burden, David A. Winkler

Année:

2005

Fichier:

PDF, 8 KB

2005

Modelling Inhalational Anaesthetics Using Bayesian Feature Selection and QSAR Modelling Methods

Journal:

ChemMedChem

Année:

2010

Langue:

english

Fichier:

PDF, 171 KB

english, 2010

Micellar electrokinetic chromatographic studies in D2O based buffer solutions

Mark Greenaway, George Okafo, David Manallack, Dr. Patrick Camilleri

Journal:

ELECTROPHORESIS

Année:

1994

Langue:

english

Fichier:

PDF, 572 KB

english, 1994

Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors

Shannon D. Zanatta, David T. Manallack, Bevyn Jarrott, Spencer J. Williams

Journal:

Paul V. Murphy, Rod E. Hubbard, David T. Manallack, John G. Montana, Richard J.K. Taylor

Année:

2009

Langue:

english

Fichier:

PDF, 227 KB

english, 2009

The synthesis of novel structural analogues of sialyl Lewisx

Journal:

Tetrahedron Letters

Année:

1998

Langue:

english

Fichier:

PDF, 240 KB

english, 1998

Neural networks in drug discovery: have they lived up to their promise?

David T. Manallack, David J. Livingstone

Journal:

European Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 258 KB

english, 1999

Arylsulphonyl hydroxamic acids: potent and selective matrix metalloproteinase inhibitors

Andrew D Baxter, Ranjev Bhogal, John Bird, John F Keily, David T Manallack, John G Montana, David A Owen, William R Pitt, Robert J Watson, Ruth E Wills

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 582 KB

english, 2001

Mercaptoacyl matrix metalloproteinase inhibitors: The effect of substitution at the mercaptoacyl moiety

Andrew D Baxter, Ranjev Bhogal, John B Bird, George M Buckley, David S Gregory, Paul C Hedger, David T Manallack, Tracy Massil, Kevin J Minton, John G Montana, Stephen Neidle, David A Owen, Robert J W

Journal:

Paul V. Murphy, Rod E. Hubbard, David T. Manallack, Ruth E. Wills, John G. Montana, Richard J.K. Taylor

Année:

1997

Langue:

english

Fichier:

PDF, 265 KB

english, 1997

The design, synthesis, and evaluation of novel conformationally rigid analogues of sialyl Lewisx

Journal:

Bioorganic & Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 1.83 MB

english, 1998

Theoretical hydrogen bonding parameters for drug design

Emanuela Gancia, John G. Montana, David T. Manallack

Journal:

Journal of Molecular Graphics and Modelling

Année:

2001

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2001

Relating biological activity to chemical structure using neural networks

David T. Manallack, David J. Livingstone

Journal:

Pest Management Science

Année:

1995

Langue:

english

Fichier:

PDF, 323 KB

english, 1995

Neural Networks in 3D QSAR

David J. Livingstone, David T. Manallack

Journal:

Patrick Camilleri, David J. Livingstone, José A. Murphy, David T. Manallack

Année:

2003

Langue:

english

Fichier:

PDF, 107 KB

english, 2003

Chiral chromatography and multivariate quantitative structure-property relationships of benzimidazole sulphoxides

Journal:

Journal of Computer-Aided Molecular Design

Année:

1993

Langue:

english

Fichier:

PDF, 473 KB

english, 1993

The use of local surface properties for molecular superimposition

David T. Manallack

Journal:

Journal of Molecular Modeling

Année:

2008

Langue:

english

Fichier:

PDF, 314 KB

english, 2008

Active site similarity between human andPlasmodium falciparumphosphodiesterases: considerations for antimalarial drug design

Brittany L. Howard, Philip E. Thompson, David T. Manallack

Journal:

Journal of Computer-Aided Molecular Design

Année:

2011

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2011

Multivariate quantitative structure-toxicity relationships in a series of dopamine mimetics

James E. Ridings, David T. Manallack, Martin R. Saunders, John A. Baldwin, David J. Livingstone

Journal:

Toxicology

Année:

1992

Langue:

english

Fichier:

PDF, 441 KB

english, 1992

COMPARISON OF THE PROPERTIES OF [3H]-d-2-AMINO-5-PHOSPHONOPENTANOIC ACID AND [3H]-dl-2-AMINO-7-PHOSPHONOHEPTANOIC ACID BINDING TO HOMOGENATES OF RAT CEREBRAL CORTEX

David T. Manallack, Kerrie-Anne M. Sheehan, Philip M. Beart

Journal:

Clinical and Experimental Pharmacology and Physiology

Année:

1989

Langue:

english

Fichier:

PDF, 680 KB

english, 1989

Regulation of σ-Receptors: High- and Low-Affinity Agonist States, GTP Shifts, and Up-Regulation by Rimcazole and 1,3-Di(2-Tolyl)guanidine

Philip M. Beart, Rbss D. O'Shea, David T. Manallack

Journal:

Journal of Neurochemistry

Année:

1989

Langue:

english

Fichier:

PDF, 1.08 MB

english, 1989

Limitations of Functional-Link Nets as Applied to QSAR Data Analysis

David T. Manallack, David J. Livingstone

Journal:

Journal of Pharmacy and Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 316 KB

english, 1994

Getting that hit: 3D database searching in drug discovery

David T. Manallack

Journal:

Drug Discovery Today

Année:

1996

Langue:

english

Fichier:

PDF, 907 KB

english, 1996

Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors

Ian M. Coupar, Helen R. Irving, David T. Manallack, Yean Y. Tan, Fadi Ayad, Juliana Di Iulio, Nathalie Tochon-Danguy, Magdy N. Iskander

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 549 KB

english, 2012

Quantitative conformational analyses predict distinct receptor sites for PCP-like and σ drugs

David T. Manallack, Philip M. Beart

Journal:

European Journal of Pharmacology

Année:

1987

Langue:

english

Fichier:

PDF, 447 KB

english, 1987

Structure–activity relationship exploration of Kv1.3 blockers based on diphenoxylate

Nguyen, William, Howard, Brittany L., Jenkins, David P., Wulff, Heike, Thompson, Philip E., Manallack, David T.

Journal:

Livingstone, David J., Manallack, David T.

Année:

2012

Langue:

english

Fichier:

PDF, 423 KB

english, 2012

Statistics using neural networks: chance effects

Journal:

Manallack, David T., Prankerd, Richard J., Nassta, Gemma C., Ursu, Oleg, Oprea, Tudor I., Chalmers, David K.

Année:

1993

Langue:

english

Fichier:

PDF, 343 KB

english, 1993

A Chemogenomic Analysis of Ionization Constants-Implications for Drug Discovery

Journal:

ChemMedChem

Année:

2013

Langue:

english

Fichier:

PDF, 1.84 MB

english, 2013

Psychotomimetic σ-opiates and PCP

David T. Manallack, Philip M. Beart, Andrew L. Gundlach

Journal:

Trends in Pharmacological Sciences

Année:

1986

Langue:

english

Fichier:

PDF, 429 KB

english, 1986

Scaffold Hopping in De Novo Design. Ligand Generation in the Absence of Receptor Information

Lloyd, David G., Buenemann, Christoph L., Todorov, Nikolay P., Manallack, David T., Dean, Philip M.

Journal:

Manallack, David T., Ellis, Dianne D., Livingstone, David J.

Année:

2004

Langue:

english

Fichier:

PDF, 124 KB

english, 2004

Analysis of linear and nonlinear QSAR data using neural networks

Journal:

Manallack, David T., Hughes, Richard A., Thompson, Philip E.

Année:

1994

Langue:

english

Fichier:

PDF, 1.07 MB

english, 1994

The Next Generation of Phosphodiesterase Inhibitors: Structural Clues to Ligand and Substrate Selectivity of Phosphodiesterases

Journal:

Manallack, David T., Beart, Philip M.

Année:

2005

Langue:

english

Fichier:

PDF, 711 KB

english, 2005

Ionic regulation of the binding of dl-2-amino-7-phosphono-[4,5-3H]heptanoic acid to synaptosome-enriched homogenates of rat cerebral cortex

Journal:

Neuroscience Letters

Année:

1986

Langue:

english

Fichier:

PDF, 366 KB

english, 1986

Homology Modeling of Human Muscarinic Acetylcholine Receptors

Thomas, Trayder, McLean, Kimberley C., McRobb, Fiona M., Manallack, David T., Chalmers, David K., Yuriev, Elizabeth

Journal:

Journal of Chemical Information and Modeling

Année:

2014

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2014

Using the β 2 -Adrenoceptor for Structure-Based Drug Design

Manallack, David T., Chalmers, David K., Yuriev, Elizabeth

Journal:

Journal of Chemical Education

Année:

2010

Langue:

english

Fichier:

PDF, 593 KB

english, 2010

Database Searching for Thymidine and Thymidylate Kinase Inhibitors Using Three-dimensional Structure-based Methods

Manallack, David T., Pitt, Will R., Herdewijn, Piet, Balzarini, Jan, De Clercq, Erik, Sanderson, Mark R., Sohi, Maninder, Wien, Frank, Munier-Lehmann, Helene, Haouz, Ahmed, Delarue, Marc

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 272 KB

english, 2002

Comparison of moonlighting guanylate cyclases: roles in signal direction?

Freihat, Lubna, Muleya, Victor, Manallack, David T., Wheeler, Janet I., Irving, Helen R.

Journal:

Biochemical Society Transactions

Année:

2014

Langue:

english

Fichier:

PDF, 518 KB

english, 2014

The Acid/Base Profile of the Human Metabolome and Natural Products

Manallack, David T., Dennis, Matthew L., Kelly, Mark R., Prankerd, Richard J., Yuriev, Elizabeth, Chalmers, David K.

Journal:

Howard, Brittany L., Harvey, Katherine L., Stewart, Rebecca J., Azevedo, Mauro F., Crabb, Brendan S., Jennings, Ian G., Sanders, Paul R., Manallack, David T., Thompson, Philip E., Tonkin, Christopher

Année:

2013

Langue:

english

Fichier:

PDF, 517 KB

english, 2013

Identification of Potent Phosphodiesterase Inhibitors that Demonstrate Cyclic Nucleotide-Dependent Functions in Apicomplexan Parasites

Journal:

ACS Chemical Biology

Année:

2015

Langue:

english

Fichier:

PDF, 3.30 MB

english, 2015

Calcium is the switch in the moonlighting dual function of the ligand-activated receptor kinase phytosulfokine receptor 1

Muleya, Victor, Wheeler, Janet I, Ruzvidzo, Oziniel, Freihat, Lubna, Manallack, David T, Gehring, Chris, Irving, Helen R

Journal:

Cell Communication and Signaling

Année:

2014

Langue:

english

Fichier:

PDF, 673 KB

english, 2014

Binding Mode Prediction of PDE4 Inhibitors: A Comparison of Modelling Methods

Neale, Diana S., Thompson, Philip E., White, Paul J., Chalmers, David K., Yuriev, Elizabeth, Manallack, David T.

Journal:

Australian Journal of Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 362 KB

english, 2010

Quantitative Structure-activity Relationships Of (+)-anatoxin-a Derivatives

Manallack, David T., Ellis, Dianne D., Thompson, Philip E., Gallagher, Timothy, Livingstone, David J.

Journal:

Natural Product Letters

Année:

1994

Langue:

english

Fichier:

PDF, 598 KB

english, 1994

Lipophilicity of Beta-Adrenocepter Antagonists: A New Classification Scheme for Clinical Use

Northfield, Susan E, Manallack, David T

Journal:

Journal of Pharmacy Practice and Research

Année:

2007

Langue:

english

Fichier:

PDF, 439 KB

english, 2007

ChemInform Abstract: The Significance of Acid/Base Properties in Drug Discovery

Manallack, David T., Prankerd, Richard J., Yuriev, Elizabeth, Oprea, Tudor I., Chalmers, David K.

Journal: